Cholesterol Biotix is a unique formulation probiotic supplement containing three natural cholesterol-lowering ingredients:
- Plant sterols (phytosterols)
- Red yeast rice extract (monascus purpureous)
- Lactobacilli probiotic bacteria.
All three ingredients work in different ways to help support cholesterol levels naturally. Plant sterols inhibit the intestinal absorption of cholesterol; red yeast rice extract (monacolin-K) reduces the production of cholesterol by the body; and lactobacilli bacteria help remove cholesterol from the body. A daily intake of at least 800mg of plant sterols helps maintain normal blood cholesterol levels. High cholesterol is a risk factor in the development of coronary heart disease.
Benefits and features:
- Suitable for Vegans
- Suitable for Vegetarians
- Contains no hydrogenated fat, animal substances, artificial preservatives, colours or flavours, added sucrose, lactose or salt, yeast or gluten.
Plant sterols, red yeast extract, microcrystalline cellulose, magnesium stearate, lactobacilli culture (L.rhamnosus, L.bulgaricus), coenzyme Q10, capsule shell (hydroxypropylmethylcellulose).
Directions for use:
Take two capsules daily, with or after a meal. Swallow with water.
How does Cholesterol Biotix help control cholesterol levels?
An intake of plant sterols can significantly reduce elevated serum levels of LDL cholesterol. The cholesterol-lowering effect of plant sterols is caused by their inhibition of intestinal cholesterol absorption. A comprehensive 2009 meta-analysis of 84 clinical studies observed that plant sterol intake resulted in an average decrease of 8.8% in LDL cholesterol levels between 8 to 12 weeks. Using a dose-response analysis, the review also demonstrated that an intake of 2000mg daily from the diet and supplements would result in a 9% decrease in LDL cholesterol.
In 7 of the studies, daily doses of 800mg – 1000mg of plant sterols observed statistically significant reductions in LDL cholesterol. The European Food Safety Authority (EFSA) has also provided a positive scientific opinion on the cholesterol lowering health claims related to plant sterol intake, and have stated that the beneficial effect is obtained with a moderate daily intake of at least 800mg.
Red Yeast Rice (Monacolin-K)
Red yeast rice extract is the product of yeast (monascus purpureous) fermented with rice. It contains several compounds collectively known as monacolins, including monacolin-K, which is formed during the fermentation process. Monacolin-K is a potent inhibitor of HMG-CoA reductase, an enzyme that triggers cholesterol production the body. As a result, monacolin-K in red yeast rice extract can inhibit the production of cholesterol in the body.
There are several clinical trials assessing the efficacy of monacolin-K in red yeast rice extract in reducing cholesterol levels. Most recently, a 2013 randomised double-blind placebo-controlled trial using 10.2mg monacolin-K daily observed a 22% reduction in LDL cholesterol after 8 weeks.
The European Food Safety Authority (EFSA) has also provided a positive scientific opinion on the cholesterol lowering health claims related to monacolin-K from red yeast rice. The opinion was based on two double blind, placebo-controlled human intervention studies, which demonstrated a significant reduction in total cholesterol concentrations in the red yeast rice treatment groups compared to the placebo groups. One of these trials observed a 27.7% reduction in LDL cholesterol in patients taking 11.5mg monacolin-K daily for 8 weeks.
Cholesterol Biotix is a natural alterative to synthetic statin (lipid-lowering) drugs. Monacolin-K has the same chemical structure as lovastatin, a widely marketed prescription statin medication. There is some data to suggest that red yeast rice (containing monacolin-K) products are a viable alternative for patients that have discontinued statin drugs due to myalgia or myopathy (muscle pains and weakness) side effects. In one clinical trial, red yeast rice extract was successfully trialled in 62 patients with a history of discontinuation of statins due to myalgia, and observed a 21% reduction in LDL cholesterol after 24 weeks.
Lactobacilli Probiotic Bacteria
There is emerging research to suggest that lactobacilli probiotic bacteria have cholesterol-lowering properties through their ability to remove cholesterol within the body. The exact cholesterol-lowering mode of action of probiotics is not yet fully understood, but it is suggested that they include the assimilation of cholesterol by the probiotic bacteria, incorporation of cholesterol into the cellular membranes of probiotic bacteria during growth, cholesterol binding to the probiotic bacterial cell wall, the conversion of cholesterol to coprostanol by probiotic bacteria, and the enzymatic deconjugation of bile.
- Keep out of reach of children.
- Store in a dry place, below 25 Degrees Celsius. Refrigeration is optional.
- Do not exceed the stated intake unless instructed by a qualified health professional.
- Food supplements should be not used as a subs
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